
.box {

    height: 384px;
    display: grid;
    grid-template-columns: 341px 218px 341px 300px;
    grid-template-rows: repeat(2, 192px);
    place-content: center;
}

.c1_3 {
    grid-column: 1/3;
    grid-row: 1/2;
}

.r1_3 {
    grid-column: 4/5;
    grid-row: 1/3;
}

.c2_4 {
    grid-column: 2/4;
    grid-row: 2/3;
}

div > div {
    width: 100%;
    height: 100%;
}